January 16, 2018 - Directorial Quotation #40: "One of the
penalties for refusing to participate in politics is that you end up
being governed by your inferiors" (Plato, Greek philosopher).
January 15, 2018 - Our Paper of the Year
2017 was published in the Nov issue of Nature Medicine by
Arai and colleagues. The work describes a new pathway regulated
by PAF acetyl hydrolase that results in the generation of omega-3
fatty acid epoxides as new lipid mediators of mast cell-mediated
January 8, 2018 - "Don't try to be a great man, just be a man
and let history make its own judgment" (Zephram Cochrane, rocket
scientist. Also a Roy Orbison fan) Winter 2018 group meeting schedule
December 28, 2017 - Our latest palmitoleic paper (to appear
the JLR) ranks 23rd, out of 43 entries, in the
"Most-Read Articles during October thru November 2017" list. Not bad
considering that our paper was first published in the Papers in
Press section on Nov 21. With this exhilarating news we say goodbye
to this year and wait for the next one, which promises to begin in a
pretty hectic way.
December 20, 2017 - It has been suggested that titanium exposure
may be harmful to the brain, in particular to glial cells, which
include the astrocytes. Astrocytes are known as rich sources of
arachidonic acid and its oxygenated metabolites. Morale of the story: if your sixth sense says no, get to
December 19, 2017 - Directorial Quotation #39: "You never know
what is enough unless you know what is more than enough" (William
Blake, English poet).
December 14, 2017 - Those who study without interest always fail
to remember that there is a pot of gold at the other end of the
rainbow. Else, those who seek petty revenge for things they do not
agree with always fail to take into account that the best revenge is
November 27, 2017 - Extra Directorial Quotation: “Wise men speak
because they have something to say; fools because they have to say
something” (Plato, Greek philosopher).
November 22, 2017 - Old conventional wisdom has it that sapienic
acid is a fatty acid present in human sebum, skin and nails. Given
our recent editorial experiences with this fatty acid, one could say
as well that there is much of it in blood, sweat
and tears. By the way, sapienic acid is also found at significant
levels in phagocytic cells; go to your favorite eicosanoid
library to check it out!
November 21, 2017 - Directorial Quotation #37: "A muleteer told
me that you do not have to get there first, you just have to know how to
get there” (José Alfredo Jiménez, Mexican king songwriter).
November 20, 2017 - Back from Brazil, where we attended the 11th
International Congress of Pharmaceutical Sciences, held at
São Paulo state. As usual, we enjoyed the warm brazilian hospitality
at its best.
November 7, 2017 - What is better to science, the paradox or the
prejudice? If we ignore the fool on the hill who counts the falling
tears that fall before his eyes, we must conclude that it has to be
October 31, 2017 - Directorial Quotation #36: "It is better to
be hated for what you are than to be loved for what you are not”
(André Gide, Nobel Laureate in Literature 1947)
October 25, 2017 - The Annual Meeting of the Spanish Biochemical
Society is being held these days in Barcelona in association with
the French and Portuguese societies. Surrounded by one hundred and
fifty-five rumors of agitation, lipins
enjoyed their fair share of exposure
October 13, 2017 - Yes, we all know that Magneto was mad, the
Titanium Man too, and the Crimson Dynamo just couldn't cut it no
more, but the most obnoxious of the trio is by far, the man in the
middle. The only man, the fool of a man in the middle.
October 11, 2017 - Amidst the blowing of increasingly stronger
scipol winds, we have learned that according to the IUPAC, 'cholesteryl
ester' is wrong. It should be 'cholesterol ester'. The term
cholesteryl should be used when referring to particular species
only, e.g. cholesteryl hexadecenoate, cholesteryl palmitoleate,
cholesteryl sapienate, etc. Thanks to the Lipid Web for that one.
September 28, 2017 - What is science policy? You ask me while
you rivet into my pupil your pupil of blue. Science policy? And
you're asking me? Science policy... it is not you, it is to forge out
laws furtively in hidden rooms (with thanks to Gustavo Adolfo for
September 25, 2017 - "It is a pleasure to be able to quote lines
to fit any occasion" (Abraham Lincoln, President of the U.S.). Fall 2017 group meeting schedule
September 20, 2017 - An unexpected role for ethanolamine
plasmalogen hydrolysis in lipopolysaccharide priming of macrophages
for enhanced arachidonic acid mobilization, coming soon to your
local eicosanoid library (a.k.a
Publications, there on the left hand side menu). By the way,
this is going to be our first paper in an Open Access journal.
September 14, 2017 - Directorial Quotation #35: "There is
no harm in repeating a good thing" (Plato, Greek philosopher).